Table 1. Administration of cyclohexamide (CH) inhibits NMD in MEFs from Coq9Q95X and Coq9R239X mice
Coq9 mRNA (CH‐treated/untreated)
Coq9 +/+ 1.54 ± 0.12
Coq9 Q95X 5.47 ± 1.14*
Coq9 R239X 21.44 ± 6.8**,##
  • The results are represented as fold increase of Coq9 mRNA levels after cyclohexamide administration. Data are expressed as the mean ± SD of five experiments in triplicates per group. One‐way ANOVA with a Tukey post hoc test. *P < 0.05; **P < 0.01; Coq9Q95X and Coq9R239X mice versus Coq9+/+ mice. ##P < 0.01; Coq9Q95X versus Coq9R239X mice. One‐way ANOVA for comparison between the three experimental groups: P = 0.0022.