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Table of Contents

01 April 2018; volume 10, issue 4

  • Commentary
  • News & Views
  • Research Articles
  • Retraction

Commentary

  • Open Access
    Trio sequencing in pediatric cancer and clinical implications
    Trio sequencing in pediatric cancer and clinical implications
    Michaela Kuhlen, Arndt Borkhardt
    Published online 05.03.2018
    • Cancer
    • Chromatin, Epigenetics, Genomics & Functional Genomics

News & Views

  • Open Access
    Co‐targeting driver pathways in prostate cancer: two birds with one stone
    Co‐targeting driver pathways in prostate cancer: two birds with one stone
    Amina Zoubeidi, Martin E Gleave
    Published online 23.03.2018
    • Cancer
    • Pharmacology & Drug Discovery

Research Articles

  • Open Access
    Dual inhibition of AKT‐mTOR and AR signaling by targeting HDAC3 in PTEN‐ or SPOP‐mutated prostate cancer
    Dual inhibition of AKT‐mTOR and AR signaling by targeting HDAC3 in <em>PTEN</em>‐ or <em>SPOP</em>‐mutated prostate cancer
    Yuqian Yan, Jian An, Yinhui Yang, Di Wu, Yang Bai, William Cao, Linlin Ma, Junhui Chen, Zhendong Yu, Yundong He, Xin Jin, Yunqian Pan, Tao Ma, Shangqian Wang, Xiaonan Hou, Saravut John Weroha, R Jeffrey Karnes, Jun Zhang, Jennifer J Westendorf, Liguo Wang, Yu Chen, Wanhai Xu, Runzhi Zhu, Dejie Wang, Haojie Huang
    Published online 09.03.2018
    • Cancer
    • Pharmacology & Drug Discovery
  • Open Access
    Sprouty2 loss‐induced IL6 drives castration‐resistant prostate cancer through scavenger receptor B1
    Sprouty2 loss‐induced IL6 drives castration‐resistant prostate cancer through scavenger receptor B1
    Rachana Patel, Janis Fleming, Ernest Mui, Carolyn Loveridge, Peter Repiscak, Arnaud Blomme, Victoria Harle, Mark Salji, Imran Ahmad, Katy Teo, Freddie C Hamdy, Ann Hedley, Niels van den Broek, Gillian Mackay, Joanne Edwards, Owen J Sansom, Hing Y Leung
    Published online 14.03.2018
    • Cancer
    • Pharmacology & Drug Discovery
  • Open Access
    Inhibition of DDR1‐BCR signalling by nilotinib as a new therapeutic strategy for metastatic colorectal cancer
    Inhibition of DDR1‐BCR signalling by nilotinib as a new therapeutic strategy for metastatic colorectal cancer
    Maya Jeitany, Cédric Leroy, Priscillia Tosti, Marie Lafitte, Jordy Le Guet, Valérie Simon, Debora Bonenfant, Bruno Robert, Fanny Grillet, Caroline Mollevi, Safia El Messaoudi, Amaëlle Otandault, Lucile Canterel‐Thouennon, Muriel Busson, Alain R Thierry, Pierre Martineau, Julie Pannequin, Serge Roche, Audrey Sirvent
    Published online 09.02.2018
    • Cancer
    • Digestive System
    • Pharmacology & Drug Discovery
  • Open Access
    An FGFR3/MYC positive feedback loop provides new opportunities for targeted therapies in bladder cancers
    An FGFR3/MYC positive feedback loop provides new opportunities for targeted therapies in bladder cancers
    Mélanie Mahe, Florent Dufour, Hélène Neyret‐Kahn, Aura Moreno‐Vega, Claire Beraud, Mingjun Shi, Imene Hamaidi, Virginia Sanchez‐Quiles, Clementine Krucker, Marion Dorland‐Galliot, Elodie Chapeaublanc, Remy Nicolle, Hervé Lang, Celio Pouponnot, Thierry Massfelder, François Radvanyi, Isabelle Bernard‐Pierrot
    Published online 20.02.2018
    • Cancer
    • Urogenital System
  • Open Access
    Tranilast directly targets NLRP3 to treat inflammasome‐driven diseases
    Tranilast directly targets NLRP3 to treat inflammasome‐driven diseases
    Yi Huang, Hua Jiang, Yun Chen, Xiaqiong Wang, Yanqing Yang, Jinhui Tao, Xianming Deng, Gaolin Liang, Huafeng Zhang, Wei Jiang, Rongbin Zhou
    Published online 12.03.2018
    • Immunology
    • Pharmacology & Drug Discovery
  • Open Access
    Role of NKp46+ natural killer cells in house dust mite‐driven asthma
    Role of NKp46<sup>+</sup> natural killer cells in house dust mite‐driven asthma
    Eline Haspeslagh, Mary J van Helden, Kim Deswarte, Sofie De Prijck, Justine van Moorleghem, Louis Boon, Hamida Hammad, Eric Vivier, Bart N Lambrecht
    Published online 14.02.2018
    • Immunology
    • Respiratory System
  • Open Access
    Counteracting the effects of TNF receptor‐1 has therapeutic potential in Alzheimer's disease
    Counteracting the effects of TNF receptor‐1 has therapeutic potential in Alzheimer's disease
    Sophie Steeland, Nina Gorlé, Charysse Vandendriessche, Sriram Balusu, Marjana Brkic, Caroline Van Cauwenberghe, Griet Van Imschoot, Elien Van Wonterghem, Riet De Rycke, Anneke Kremer, Saskia Lippens, Edward Stopa, Conrad E Johanson, Claude Libert, Roosmarijn E Vandenbroucke
    Published online 22.02.2018
    • Immunology
    • Neuroscience
    • Pharmacology & Drug Discovery
  • Open Access
    An allosteric inhibitor of Mycobacterium tuberculosis ArgJ: Implications to a novel combinatorial therapy
    An allosteric inhibitor of <em>Mycobacterium tuberculosis</em> ArgJ: Implications to a novel combinatorial therapy
    Archita Mishra, Ashalatha S Mamidi, Raju S Rajmani, Ananya Ray, Rajanya Roy, Avadhesha Surolia
    Published online 26.02.2018
    • Microbiology, Virology & Host Pathogen Interaction
    • Pharmacology & Drug Discovery
  • Open Access
    Human ALPI deficiency causes inflammatory bowel disease and highlights a key mechanism of gut homeostasis
    Human ALPI deficiency causes inflammatory bowel disease and highlights a key mechanism of gut homeostasis
    Marianna Parlato, Fabienne Charbit‐Henrion, Jie Pan, Claudio Romano, Rémi Duclaux‐Loras, Marie‐Helene Le Du, Neil Warner, Paola Francalanci, Julie Bruneau, Marc Bras, Mohammed Zarhrate, Bernadette Bègue, Nicolas Guegan, Sabine Rakotobe, Nathalie Kapel, Paola De Angelis, Anne M Griffiths, Karoline Fiedler, Eileen Crowley, Frank Ruemmele, Aleixo M Muise, Nadine Cerf‐Bensussan
    Published online 22.03.2018
    • Digestive System
    • Genetics, Gene Therapy & Genetic Disease
    • Metabolism

Retraction

  • Open Access
    Retraction: “Haemophilus influenzae responds to glucocorticoids used in asthma therapy by modulation of biofilm formation and antibiotic resistance”
    Published online 12.03.2018
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In this Issue
Volume 10, Number 4
01 April 2018 | pp -
EMBO Molecular Medicine: 10 (4)
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