Pharmacology & Drug Discovery

Open Access
MG132‐induced progerin clearance is mediated by autophagy activation and splicing regulation

Karim Harhouri, Claire Navarro, Danielle Depetris, Marie‐Geneviève Mattei, Xavier Nissan, Pierre Cau, Annachiara De Sandre‐Giovannoli, Nicolas Lévy
Published online 03.07.2017
Open Access
Synergistic antibacterial effect of silver and ebselen against multidrug‐resistant Gram‐negative bacterial infections

Lili Zou, Jun Lu, Jun Wang, Xiaoyuan Ren, Lanlan Zhang, Yu Gao, Martin E Rottenberg, Arne Holmgren
Published online 12.06.2017
- Microbiology, Virology & Host Pathogen Interaction
- Pharmacology & Drug Discovery
Open Access
CDK4 phosphorylation status and a linked gene expression profile predict sensitivity to palbociclib

Eric Raspé, Katia Coulonval, Jaime M Pita, Sabine Paternot, Françoise Rothé, Laure Twyffels, Sylvain Brohée, Ligia Craciun, Denis Larsimont, Véronique Kruys, Flavienne Sandras, Isabelle Salmon, Steven Van Laere, Martine Piccart, Michail Ignatiadis, Christos Sotiriou, Pierre P Roger
Published online 31.05.2017
Open Access
γ‐Secretase inhibitors in cancer clinical trials are pharmacologically and functionally distinct

Yong Ran, Fokhrul Hossain, Antonio Pannuti, Christian B Lessard, Gabriela Z Ladd, Joo In Jung, Lisa M Minter, Barbara A Osborne, Lucio Miele, Todd E Golde
Published online 24.05.2017
Open Access
A clinical and mechanistic study of topical borneol‐induced analgesia

Shu Wang, Dan Zhang, Jinsheng Hu, Qi Jia, Wei Xu, Deyuan Su, Hualing Song, Zhichun Xu, Jianmin Cui, Ming Zhou, Jian Yang, Jianru Xiao
Published online 10.04.2017
- Neuroscience
- Pharmacology & Drug Discovery
Open Access
Ferrochelatase is a therapeutic target for ocular neovascularization

Halesha D Basavarajappa, Rania S Sulaiman, Xiaoping Qi, Trupti Shetty, Sardar Sheik Pran Babu, Kamakshi L Sishtla, Bit Lee, Judith Quigley, Sameerah Alkhairy, Christian M Briggs, Kamna Gupta, Buyun Tang, Mehdi Shadmand, Maria B Grant, Michael E Boulton, Seung‐Yong Seo, Timothy W Corson
Published online 04.04.2017
Open Access
An intranasally delivered peptide drug ameliorates cognitive decline in Alzheimer transgenic mice

Yu‐Sung Cheng, Zih‐ten Chen, Tai‐Yan Liao, Chen Lin, Howard C‐H Shen, Ya‐Han Wang, Chi‐Wei Chang, Ren‐Shyan Liu, Rita P‐Y Chen, Pang‐hsien Tu
Published online 29.03.2017
- Neuroscience
- Pharmacology & Drug Discovery
Open Access
Delivery is key: lessons learnt from developing splice‐switching antisense therapies

Caroline Godfrey, Lourdes R Desviat, Bård Smedsrød, France Piétri‐Rouxel, Michela A Denti, Petra Disterer, Stéphanie Lorain, Gisela Nogales‐Gadea, Valentina Sardone, Rayan Anwar, Samir EL Andaloussi, Taavi Lehto, Bernard Khoo, Camilla Brolin, Willeke MC van Roon‐Mom, Aurélie Goyenvalle, Annemieke Aartsma‐Rus, Virginia Arechavala‐Gomeza
Published online 13.03.2017
- Pharmacology & Drug Discovery
Open Access
Targeting Toxoplasma gondii CPSF3 as a new approach to control toxoplasmosis

Andrés Palencia, Alexandre Bougdour, Marie‐Pierre Brenier‐Pinchart, Bastien Touquet, Rose‐Laurence Bertini, Cristina Sensi, Gabrielle Gay, Julien Vollaire, Véronique Josserand, Eric Easom, Yvonne R Freund, Hervé Pelloux, Philip J Rosenthal, Stephen Cusack, Mohamed‐Ali Hakimi
Published online 01.02.2017
- Microbiology, Virology & Host Pathogen Interaction
- Pharmacology & Drug Discovery
Open Access
PERK activation mitigates tau pathology in vitro and in vivo

Julius Bruch, Hong Xu, Thomas W Rösler, Anderson De Andrade, Peer‐Hendrik Kuhn, Stefan F Lichtenthaler, Thomas Arzberger, Konstanze F Winklhofer, Ulrich Müller, Günter U Höglinger
Published online 01.02.2017
- Neuroscience
- Pharmacology & Drug Discovery

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