Immunology

Open Access
Glucocorticoid‐induced microRNA‐511 protects against TNF by down‐regulating TNFR1

Leen Puimège, Filip Van Hauwermeiren, Sophie Steeland, Sara Van Ryckeghem, Jolien Vandewalle, Sofie Lodens, Lien Dejager, Sofie Vandevyver, Jan Staelens, Steven Timmermans, Roosmarijn E Vandenbroucke, Claude Libert
Published online 20.05.2015
- Immunology
Open Access
When natural mutants do not fit our expectations: the intriguing case of patients with XRCC4 mutations revealed by whole‐exome sequencing

Jean‐Pierre de Villartay
Published online 11.05.2015
Open Access
Antigen delivery by filamentous bacteriophage fd displaying an anti‐DEC‐205 single‐chain variable fragment confers adjuvanticity by triggering a TLR9‐mediated immune response

Rossella Sartorius, Luciana D'Apice, Maria Trovato, Fausta Cuccaro, Valerio Costa, Maria Giovanna De Leo, Vincenzo Manuel Marzullo, Carmelo Biondo, Sabato D'Auria, Maria Antonietta De Matteis, Alfredo Ciccodicola, Piergiuseppe De Berardinis
Published online 17.04.2015
- Immunology
- Microbiology, Virology & Host Pathogen Interaction
Open Access
ADAP and SKAP55 deficiency suppresses PD‐1 expression in CD8⁺ cytotoxic T lymphocytes for enhanced anti‐tumor immunotherapy

Chunyang Li, Weiyun Li, Jun Xiao, Shaozhuo Jiao, Fei Teng, Shengjie Xue, Chi Zhang, Chun Sheng, Qibin Leng, Christopher E Rudd, Bin Wei, Hongyan Wang
Published online 07.04.2015
- Cancer
- Immunology
Open Access
Low‐dose TNF augments fracture healing in normal and osteoporotic bone by up‐regulating the innate immune response
$Low‐dose TNF augments fracture healing in normal and osteoporotic bone by up‐regulating the innate immune response$

James K Chan, Graeme E Glass, Adel Ersek, Andrew Freidin, Garry A Williams, Kate Gowers, Ana I Espirito Santo, Rosemary Jeffery, William R Otto, Richard Poulsom, Marc Feldmann, Sara M Rankin, Nicole J Horwood, Jagdeep Nanchahal
Published online 14.03.2015
- Immunology
- Musculoskeletal System
Open Access
Phospholipid oxidation generates potent anti‐inflammatory lipid mediators that mimic structurally related pro‐resolving eicosanoids by activating Nrf2

Peter Bretscher, Julian Egger, Abdijapar Shamshiev, Martin Trötzmüller, Harald Köfeler, Erick M Carreira, Manfred Kopf, Stefan Freigang
Published online 13.03.2015
- Immunology
- Pharmacology & Drug Discovery
Open Access
Inhibition of lethal inflammatory responses through the targeting of membrane‐associated Toll‐like receptor 4 signaling complexes with a Smad6‐derived peptide

Youn Sook Lee, Jin Seok Park, Su Myung Jung, Sang‐Doo Kim, Jun Hwan Kim, Jae Young Lee, Kyeong Cheon Jung, Mizuko Mamura, Sangho Lee, Seong‐Jin Kim, Yoe‐Sik Bae, Seok Hee Park
Published online 12.03.2015
- Immunology
Open Access
Anti‐BDCA2 monoclonal antibody inhibits plasmacytoid dendritic cell activation through Fc‐dependent and Fc‐independent mechanisms

Alex Pellerin, Karel Otero, Julie M Czerkowicz, Hannah M Kerns, Renée I Shapiro, Ann M Ranger, Kevin L Otipoby, Frederick R Taylor, Thomas O Cameron, Joanne L Viney, Dania Rabah
Published online 11.03.2015
- Immunology
- Pharmacology & Drug Discovery
Open Access
A high‐throughput RNAi screen for detection of immune‐checkpoint molecules that mediate tumor resistance to cytotoxic T lymphocytes

Nisit Khandelwal, Marco Breinig, Tobias Speck, Tillmann Michels, Christiane Kreutzer, Antonio Sorrentino, Ashwini Kumar Sharma, Ludmila Umansky, Heinke Conrad, Isabel Poschke, Rienk Offringa, Rainer König, Helga Bernhard, Arthur Machlenkin, Michael Boutros, Philipp Beckhove
Published online 17.02.2015
Open Access
Hepatic stellate cell‐expressed endosialin balances fibrogenesis and hepatocyte proliferation during liver damage

Carolin Mogler, Matthias Wieland, Courtney König, Junhao Hu, Anja Runge, Claudia Korn, Eva Besemfelder, Katja Breitkopf‐Heinlein, Dorde Komljenovic, Steven Dooley, Peter Schirmacher, Thomas Longerich, Hellmut G Augustin
Published online 13.02.2015

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